Oncology
Central nervous system
Encyclopedia entries in Central nervous system.
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Central nervous system
Diffuse midline glioma
Diffuse midline glioma, H3 K27-altered, is an aggressive WHO grade 4 tumour of the brainstem, thalamus, or spinal cord. This entry covers children, DIPG, and radiotherapy.
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Central nervous system
Ependymoma
Ependymoma is a glial tumour that usually grows from the lining of the ventricles or the central canal of the spinal cord. This entry covers posterior-fossa tumours in children and surgery.
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Central nervous system
Glioblastoma
Glioblastoma is the most common malignant primary brain tumour in adults, now defined as IDH-wildtype WHO grade 4. This entry covers maximal resection, radiotherapy, and temozolomide.
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Central nervous system
IDH-mutant astrocytoma
IDH-mutant astrocytoma is a diffuse glioma of adults, defined by an IDH mutation and no 1p/19q codeletion. This entry covers grade, CDKN2A/B, and surgery plus adjuvant therapy.
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Central nervous system
Medulloblastoma
Medulloblastoma is the most common malignant brain tumour of children and starts in the cerebellum. This entry covers molecular groups, surgery, CSI, and chemotherapy.
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Central nervous system
Meningioma
Meningioma is a tumour of the meninges, usually benign and slow-growing. This entry covers incidental findings, WHO grade, and when to operate or watch.
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Central nervous system
Oligodendroglioma
Oligodendroglioma is an IDH-mutant diffuse glioma defined by 1p/19q codeletion. This entry covers seizures, calcified frontal tumours, and PCV or temozolomide.
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Central nervous system
Pilocytic astrocytoma
Pilocytic astrocytoma is a WHO grade 1 glioma, the most common brain tumour of children, often in the cerebellum. This entry covers the mural nodule, BRAF, and surgery.
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Central nervous system
Primary CNS lymphoma
Primary CNS lymphoma is usually a diffuse large B-cell lymphoma confined to the brain, eyes, or CSF. This entry covers immunocompetent adults, steroids, and methotrexate.
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Central nervous system
Vestibular schwannoma
Vestibular schwannoma is a benign tumour of the hearing and balance nerve. This entry covers unilateral hearing loss, NF2, observation, radiosurgery, and microsurgery.