Oncology
Childhood
Encyclopedia entries in Childhood.
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Acute leukaemias
ALL
Acute lymphoblastic leukaemia (ALL) is a fast-growing cancer of lymphoid blasts in blood and marrow. This entry covers children, adults, and CNS-directed therapy.
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Childhood
Burkitt lymphoma
Burkitt lymphoma is a highly aggressive B-cell lymphoma with MYC rearrangement. This entry covers endemic, sporadic, and immunodeficiency-related forms.
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Central nervous system
Diffuse midline glioma
Diffuse midline glioma, H3 K27-altered, is an aggressive WHO grade 4 tumour of the brainstem, thalamus, or spinal cord. This entry covers children, DIPG, and radiotherapy.
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Central nervous system
Ependymoma
Ependymoma is a glial tumour that usually grows from the lining of the ventricles or the central canal of the spinal cord. This entry covers posterior-fossa tumours in children and surgery.
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Childhood
Hepatoblastoma
Hepatoblastoma is the most common liver cancer of early childhood. This entry covers PRETEXT staging, cisplatin chemotherapy, and surgery or transplant.
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Central nervous system
Medulloblastoma
Medulloblastoma is the most common malignant brain tumour of children and starts in the cerebellum. This entry covers molecular groups, surgery, CSI, and chemotherapy.
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Childhood
Ovarian germ cell tumours
Malignant ovarian germ cell tumours are rare cancers of young women. This entry covers dysgerminoma, yolk sac tumour, immature teratoma, and fertility-sparing treatment.
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Central nervous system
Pilocytic astrocytoma
Pilocytic astrocytoma is a WHO grade 1 glioma, the most common brain tumour of children, often in the cerebellum. This entry covers the mural nodule, BRAF, and surgery.
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Childhood
Undifferentiated rhabdomyosarcoma
A rare aggressive sarcoma of skeletal-muscle lineage that lacks clear rhabdomyoblastic features. It is a diagnosis of exclusion among rhabdomyosarcomas.